Publications

Selected Research Publications
[Click here for a full list on Google Scholar]

 

1.  Salar, S., Silletti, S., & Schubot, F. D. (2025). Evidence of Bidirectional Transmembrane Signaling by the Sensor Histidine Kinase GacS from Pseudomonas aeruginosa. Journal of Biological Chemistry, 108521.
2.  Salar, S., Ball, N. E., Baaziz, H., Nix, J. C., Sobe, R. C., Compton, K. K., … & Schubot, F. D. (2023). The structural analysis of the periplasmic domain of Sinorhizobium meliloti chemoreceptor McpZ reveals a novel fold and suggests a complex mechanism of transmembrane signaling. Proteins: Structure, Function, and Bioinformatics, 91(10), 1394-1406.
3.  Rebholz, Z., Shewade, L., Kaler, K., Larose, H., Schubot, F., Tholl, D., … & O’Maille, P. E. (2023). Emergence of terpene chemical communication in insects: Evolutionary recruitment of isoprenoid metabolism. Protein Science, 32(5), e4634.
4.  Kaler, K. M. R., Nix, J. C., & Schubot, F. D. (2021). RetS inhibits Pseudomonas aeruginosa biofilm formation by disrupting the canonical histidine kinase dimerization interface of GacS. Journal of Biological Chemistry, 297(4).
5.  Shrestha, M., Bernhards, R. C., Fu, Y., Ryan, K., & Schubot, F. D. (2020). Backbone interactions between transcriptional activator ExsA and anti-activator ExsD facilitate regulation of the type III secretion system in Pseudomonas aeruginosa. Scientific Reports, 10(1), 9881.
6.  Mancl, J. M., Ray, W. K., Helm, R. F., & Schubot, F. D. (2019). Helix cracking regulates the critical interaction between RetS and GacS in Pseudomonas aeruginosa. Structure, 27(5), 785-793.
7.  Shrestha, M., Compton, K. K., Mancl, J. M., Webb, B. A., Brown, A. M., Scharf, B. E., & Schubot, F. D. (2018). Structure of the sensory domain of McpX from Sinorhizobium meliloti, the first known bacterial chemotactic sensor for quaternary ammonium compounds. Biochemical Journal, 475(24), 3949-3962.
8.  Black, W. P., Wang, L., Jing, X., Saldaña, R. C., Li, F., Schubot, F. D., … & Yang, Z. (2017). The type IV pilus assembly ATPase PilB functions as a signaling protein to regulate exopolysaccharide production in Myxococcus xanthus. Scientific reports, 7(1), 7263.
9. Mancl, J. M., Black, W. P., Robinson, H., Yang, Z., & Schubot, F. D. (2016). Crystal structure of a type IV pilus assembly ATPase: insights into the molecular mechanism of PilB from Thermus thermophilus. Structure, 24(11), 1886-1897.
10. Shrestha, M., Xiao, Y., Robinson, H., & Schubot, F. D. (2015). Structural analysis of the regulatory domain of ExsA, a key transcriptional regulator of the type three secretion system in Pseudomonas aeruginosa. PLoS One, 10(8), e0136533.